Friday, April 29, 2016

My Two Cents

This Transgenders in Bathrooms bullshit has got to stop.
The only thing this accomplishes is exiling disadvantaged people into their homes.

The only people worried about this are old men. 
I have been going in ladies bathrooms my entire life.  There is nothing sketchy going on in there.  We go in the stalls, do our business and then come out and wash our hands.  Maybe every once in a while there is a make-up or garment failure being addressed.   That's all.
You nasty old men have spent too much time amongst your own kind and are imagining things that don't exist.

I have two suggestions:

I am quite sure that Any Man who has a small daughter would be welcome to stand at the entrance and wait for her.   It's not a big deal.    All you will see is handwashing.    Just explain yourself.   We do speak human languages you know.

However, I really like the idea of "Take your Man into the Ladies Room Day".
Some Saturday we should all take the freaked out dads and grampas to the mall or stadium and show them the Scary Room.

Interesting

Hot Sauce seem to be in the news lately.

Hot Sauce contains capsaicin, the spicy part of some peppers.

High levels of capsaicin kill strep bacteria, low levels inhibit it's virility.

I will now put Salsa Addiction on my list of secondary symptoms.

Monday, April 25, 2016

Yes, This.

Maybe Donald Trump has really lost his mind: What if the GOP frontrunner isn’t crazy, but simply not well? 

Leaving aside the fact that all mental illness is simply illness...

Donald Trump is bacteremic and probably septic.
He has none of his natural teeth, and his adenoids are so infected they are the most prominent thing on his face.   See the large red swellings on either side of his nose.
That spray tan and the fake teeth are to cover up the appalling state of his health.


That much head infection causes all kinds of mental symptoms, and he exhibits most of them.  
Mainly impulsivity, memory loss and verbal impairment.
Kind of like his followers.

edit:  just thinking-  in iTrump'a natural state-
His hair is orange, his teeth are yellow, and his skin is white.

A couple or three

Patients at high risk for psychiatric symptoms after a stay in the intensive care unit

Yes, if you aren't already septic when you go in-  they will be sure to cut you and poke you and put lots of holes in your epithelium.   And expose you to all those antibiotic resistant microbes that live in hospitals.   And put you on a glucose drip too.
 

Lower-carb diet slows growth of aggressive brain tumor in mouse models
A high-fat, low-carbohydrate diet that included a coconut oil derivative helped reduce the growth of glioblastoma tumor cells and extended lifespan in mouse models by 50 percent, researchers found.
Glioblastoma, the most common brain tumor in adults, has no effective long-term treatment and on average, patients live for 12 to 15 months after diagnosis, according to the National Cancer Institute.
The findings are a new twist on an old idea: The so-called ketogenic diet has been used for nearly 90 years to help reduce epileptic seizures. Now, a high-fat, low-carbohydrate version of the ketogenic diet has been shown to slow glioblastoma tumors by cutting back on the energy supply they need to thrive, said Brent Reynolds, Ph.D. A glioblastoma tumor requires large amounts of energy as it grows, and the dietary intervention works by drastically limiting the tumor's supply of glucose, Reynolds said.   citation

HIV defies attempt to edit virus out of human cells with CRISPR
Vanquishing HIV just got that little bit harder. A promising technique to weaken the virus has in some cases made it stronger.

Saturday, April 23, 2016

This is Why

US suicide rate jumps 24 percent since 1999
The rate increased by about one percent a year from 1999, then accelerated to two percent annually from 2006 to 2014, said the findings by the Centers for Disease Control and Prevention's National Center for Health Statistics.
The rise was seen among both males and females and for all ages 10-74, said the report.
The biggest jump was among girls aged 10-14, whose suicide rate tripled from 0.5 per 100,000 people in 1999 to 1.5 per 100,000 in 2014.
Good grief, adolescent girls?   The ones you are stuffing full of carbs?   Those girls?

Seeing as psychs can't replicate their research, and mental illness seems to be getting RAPIDLY WORSE- it's now completely plausible that their entire underlying premise is wrong. 
There is no reason to believe they are providing any value to society.

Friday, April 22, 2016

Dear Joe Arpaio

How dare you tweet this bullshit:
“Condolences to family of Prince, who allegedly died of overdose. Just celebrated 20 yrs of drug rehab in my jails. Drugs destroying our nation.”

There is no possible way your wreck of a body could still function without some high grade drug products.   You are your own worst argument.

And you are not providing drug rehab for your inmates- you are practicing barbaric forms of human cruelty under the guise of righteousness.    

Demented old men making self-serving assumptions about everything-  That is what is tearing apart this country.

When you die, everyone will dance too.   Just not for the same reasons.
I for one, will make a special pilgrimage to spit on your grave.

Thursday, April 21, 2016

Ahem

Study suggests immune response to flu causes death in older people, not the virus

Old Song of the Day

Let's Go Crazy
RIP Prince.    

Same as it ever was

Sober is the new drunk: why millennials are ditching bar crawls for juice crawls 

Because their metabolisms are already too fucked up by pharmaceuticals for actual alcohol?
Because fructose and various spices have pretty much the same metabolic effect as alcohol?
Because they believe it's healthy and like to feel self-righteous?
Because doctors suck???

Things I Am Reading

It might not be dementia: How Big Pharma is harming our senior citizens
People are taking more drugs than ever before and not always aware of their side effects and interactions. This “polypharmacy” can produce everything from falls and accidents to behavior that is quickly termed dementia in the elderly, even when it is clearly from drug effects.

Every City Has a Unique Microbial “Fingerprint”
From architecture to microbes, every city is different

Pancreatic cancer risk tied to specific mouth bacteria
Specifically, researchers found that men and women whose oral microbiomes included Porphyromonas gingivalis had an overall 59 percent greater risk of developing pancreatic cancer.

Chlorhexidine Tolerance and Its Role in Healthcare-Associated Infections
This requires a free subscription, but basically it says that about half of Staph aureus samples taken in a hospital were resistant to Chlorhexidine.   And the more they used it the higher that number was...

Telomere length tied to higher myocardial infarction risk 
Chronic endotoxemia shortens telomeres.  

Parasitic infection enables helpful bacteria to displace harmful ones
Infection with worms may counter inflammatory bowel diseases by triggering immune responses that change the mix of bacteria, or microbiome, in the gut.

Doctors for Cannabis Regulation
Yeah, but they're still claiming it's not healthy.  Just that criminalization is stupid.
All the research shows the opposite:   Marijuana has many beneficial metabolic and neurological effects.

Wednesday, April 20, 2016

Paging Dr. Mignot

The ASO2 adjuvant in the Pandemrix vaccine is made from gram negative endotoxin.
But you should probably already know that.

Tuesday, April 19, 2016

Brain Fart for Prez

 Donald Trump mixes up ‘9/11’ with ‘7-Eleven
 ’“I wrote this out, and it’s very close to my heart,” he said at the outset of his remarks on Buffalo on Monday evening. “Because I was down there and I watched our police and our firemen down at 7/11, down at the World Trade Center right after it came down. And I saw the greatest people I’ve ever seen in action.”
Either he wants to lose, or he has some pretty severe Aphasia.
Both are good reasons not to vote for him.

Sunday, April 17, 2016

A Little Medical History

The Killer Hiding in the CDC Map

What caused Haiti’s cholera epidemic? The CDC museum knows but won’t say.
Admitting that soldiers are the source might support the conclusion that Armies are (and always have been) a primary vector of human infection around the planet
That would totally mess up the old-boy-club's delusions of righteousness... can't have that.

Wednesday, April 13, 2016

As I Was Saying

Woman dies in parking lot of Southfield Dental Care after removal of her teeth
The 46-year-old patient, April Walters, had respiratory illnesses, sarcoidosis, COPD, diabetes, asthma and high blood pressure, and she was also on oxygen. None of those conditions were life threatening, still she died due to some cause yet to be discovered. The family of April is seeking reason behind her death, soon after the dental appointment.
Money Quote:
Dr. Rabban only removed 16 teeth instead of 18 and told Cutright to take her sister to see a doctor and get her heart checked out.
This lady was chronically ill and now is dead because the medical establishment separates dental work from all other care.

A few for you

This study could have reshaped the American diet 40 years ago. But it was never fully published until now.
A massive government-funded experiment on fatty foods challenges the conventional advice about what is healthy.

Increase in coffee consumption could provide protective effect in non-alcoholic fatty liver disease
A daily dose of coffee could improve several key markers of non-alcoholic fatty liver disease by reducing permeability of the gut

 Is Acetaminophen hampering our ability to notice errors?

Tuesday, April 12, 2016

PaleoEpidemiology

Neanderthals may have died of diseases carried by humans from Africa
New research challenges the idea that the spread of infectious diseases exploded as agriculture evolved 8,000 years ago

STIs may have driven ancient humans to monogamy, study says
The shift away from polygamy to monogamy with the dawn of agriculture could be down to the impact of sexually transmitted infections in communities

Monday, April 11, 2016

Required Reading

Sepsis: A Silent Killer
Until recently, the CDC failed to even mention sepsis in it’s A–Z index of medical terms.
 I will now go bash my head on a wall for a while.


Bonus Article:
Suicide risk can be intercepted in the emergency department
Higher rates of suicidal thoughts in the emergency room.  Can't imagine why....

Oh My Head Hurts Update
Bruce Shisheesh, the chief of the Attawapiskat First Nation community, said 11 people attempted to take their own lives on Saturday, prompting him to declare a state of emergency.
He tweeted that the regional Weeneebayko Health Authority was flying in a crisis team, mental health nurses and social workers, and that he was waiting for Ontario's minister of health to deliver more emergency workers to the area.

AYFKM????  Send some fucking doctors!!!!!
Those people are SICK.  You have a real epidemic going on under your noses!!!!!!!

Saturday, April 9, 2016

Things that make me twitch

The emergence of neonatal group B streptococcal infections explained
Scientists from the Institut Pasteur have recently revealed the cause behind the emergence in the 1960s of neonatal infections due to group B streptococcus. These findings, published in Nature Communications on August 4, 2014, prove that the sudden emergence of infections caused by this bacterium resulted from the widespread use of an antibiotic, tetracycline, from the 1950s onwards.
Oh me, oh my.

Old Folks

A Paleolithic-type diet may help reduce future risk of diabetes and cardiovascular disease
"Eating a Paleolithic-type diet without calorie restriction significantly improved the fatty acid profile associated with insulin sensitivity, and it reduced abdominal adiposity and body weight in obese postmenopausal women," said lead study author Caroline Blomquist. "A Paleolithic-type diet, high in polyunsaturated fatty acids, may have long-term beneficial effects on obesity-related disorders, including reduced risk for diabetes and cardiovascular disease."

Common prostate cancer treatments suppress immune response and may promote relapse
Prostate cancer patients and their doctors may want to think twice about the best timing for chemotherapy or radiation therapy in conjunction with a common nonsurgical treatment, based on international research findings led by UT Southwestern Medical Center investigators.
Researchers using mouse models found that many medical androgen deprivation therapies (ADTs) - the most commonly used nonsurgical treatments for prostate cancer - may suppress patients' adaptive immune responses, preventing immunotherapies from working if both treatments are used but not sequenced properly. ADTs are anti-hormone therapies that decrease the body's levels of androgens, the type of hormone that is required for prostate cancer to survive and grow.

Friday, April 8, 2016

Cause and Effect

Number of adults with diabetes has quadrupled since 1980: WHO

Yes, that's because in 1977 the USDA told us to cut back on fat and eat more carbs.
It had the exact opposite effect that they told us it would.   Made everything much, much, worse.

Monday, April 4, 2016

HeadDeskHeadDeskHeadDesk

The Influence Of Endotoxin Administration On The Nutritional Requirements Of Mice
Albino mice lose weight within 24 hours following administration of bacterial endotoxin. The initial weight loss is proportional to the dose of endotoxin injected only when this dose is very small. The loss during the 1st day reaches a maximum with 10 to 30 µg of endotoxin; larger doses increase the duration of the overall effect. The rate at which mice regain weight after administration of endotoxin is markedly influenced by the composition of the diet. Recovery was rapid and complete within a few days when the animals were fed commercial pellets or a semisynthetic diet containing casein. In contrast, recovery was slow and incomplete when wheat gluten was used instead of casein in the diet. The deleterious effect of the gluten diet was less marked in older than in younger animals, probably because the latter have less exacting nutritional requirements. It was postulated that the failure of endotoxin-treated mice to regain weight when fed the gluten diet was due to the fact that this protein is low in certain amino acids. In fact, rapid and complete recovery from the weight loss uniformly occurred when the gluten diet was supplemented with proper amounts of lysine and threonine. The composition of the diet did not influence the extent of the initial loss of weight caused by endotoxin, nor did it prevent the animals from developing tolerance to this substance.
Yeah, that article was published in 1965.  Fifty freakin years ago.

Sunday, April 3, 2016

Correlation Games

Anxiety increases the risk of gastrointestinal infection and long-term complications

In December 2010, the Belgian communities of Schelle and Hemiksem in the province of Antwerp faced an outbreak of gastroenteritis, with more than 18,000 people exposed to contaminated drinking water.

The scientists found that individual with higher levels of anxiety or depression prior to the water contamination developed gastrointestinal infections of increased severity. The same individuals also had an increased risk of developing the long-term complication of irritable bowel syndrome, with intermittent abdominal cramps, diarrhea or constipation a year after the initial contamination.
"Irritable Bowel Syndrome is a condition of chronic abdominal pain and altered bowel movements. This is a common condition with large socio-economic costs, yet there is so much that still remains to be discovered about the causes. Our investigation found that that anxiety or depression alters the immune response towards a gastrointestinal infection, which can result in more severe symptoms and the development of chronic irritable bowel syndrome."
 "These results once again emphasize the importance of mental health care and social support services. We need to understand that health, society and economics are not independent, and ignoring depression and anxiety results in higher long-term medical costs."
My turn:   This is unmitigated Brain Eating Bullshit.  Social support services would do nothing to change this outcome.

Alternate explanation:   Preexisting Gastrointestinal Illness.  
Anxiety and Depression are SYMPTOMS OF INFECTION.  Those people were already sick.
So when they drank contaminated water, well....  they got sicker.

Article Roundup

To keep or not to keep a hookworm
A very interesting study showing that sometimes it is better to have a chronic infection than to destroy yourself trying to eliminate it.

History of chicken pox may reduce risk of brain cancer later in life
Another interesting example of infection altering immune response.

Fat tissue in energy saving mode
Scientists have discovered brain cells that not only tell hungry mice to search for food, but also to limit blood sugar use by the brown fat tissue. This could ensure the survival of mice when they cannot find enough to eat.

‘Concern’ over GPs prescribing ‘unnecessary’ antibiotics for toothache
Let's have some concern for dental care not being prioritized or insured, huh?

Chemical in antibacterial soap may disrupt mix of organisms in digestive tract
Do NOT use antibacterial soap.   It facilitates antimicrobial resistance.

People who never forget their past could have unique kind of OCD
It sounds like a horrible fate.  There are so many things I am glad I have forgotten.

Are we what we eat?
Evidence of vegetarian diet permanently shaping the human genome.  These people are losing the ability to metabolize animal fats.

Friday, April 1, 2016

See the Vortex

The Impossibility of Managing a Chronic Disease While Homeless

Living on the street, even something as simple as finding a place to store medicine can be an insurmountable challenge.