Tuesday, May 30, 2017

Predictable

"He now lives within himself, which is a dangerous place for Donald Trump to be," says someone who speaks with the President. "I see him emotionally withdrawing. He's gained weight."
Yes, we are definitely in the downward portion of the metabolic and mental symptoms.
Anything is possible now.

Monday, May 29, 2017

This is Why

Because I think it would be beneficial if this young man were informed that this is exactly the kind of wound that can cause invasive chronic infection and neurological symptoms.

Zombie Tourism

Museum of Snoring

My peeps!  Archiving medical sleep devices!  Bwa ha ha ha ha!

Thoughts on Memorial Day




Saturday, May 27, 2017

Ahem

The brain starts to eat itself after chronic sleep deprivation

Sleep loss in mice sends the brain’s immune cells into overdrive. This might be helpful in the short term, but could increase the risk of dementia in the long run
One type of glial cell, called an astrocyte, prunes unnecessary synapses in the brain to remodel its wiring. Another type, called a microglial cell, prowls the brain for damaged cells and debris.
Bellisi’s team found that after an undisturbed sleep, astrocytes appeared to be active in around 6 per cent of the synapses in the brains of the well-rested mice. But astrocytes seemed to be more active in sleep-deprived mice – those that had lost eight hours of sleep showed astrocyte activity in around 8 per cent of their synapses, while the cells were active in 13.5 per cent of the synapses of the chronically sleep-deprived animals.
This suggests that sleep loss can trigger astrocytes to start breaking down more of the brain’s connections and their debris. “We show for the first time that portions of synapses are literally eaten by astrocytes because of sleep loss,” says Bellesi.
Similarly-

Century-old drug as potential new approach to autism

In a small, randomized Phase I/II clinical trial (SAT1), researchers say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, was safely administered to children with autism spectrum disorder (ASD), who subsequently displayed measurable, but transient, improvement in core symptoms of autism.

Naviaux, who is co-director of the Mitochondrial and Metabolic Disease Center at UC San Diego, believes that ASD -- and several other chronic conditions, including chronic fatigue syndrome and some autoimmune disorders -- are caused by metabolic dysfunction or impaired communication between cells in the brain, gut and immune system.

Specifically, this dysfunction is caused by abnormal persistence of the cell danger response (CDR), a natural and universal cellular reaction to injury or stress. "The purpose of CDR is to help protect the cell and jump-start the healing process," said Naviaux, by essentially causing the cell to harden its membranes, cease interaction with neighbors and withdraw within itself until the danger has passed.

"But sometimes CDR gets stuck," Naviaux said. "This prevents completion of the natural healing cycle and can permanently alter the way the cell responds to the world. When this happens, cells behave as if they are still injured or in imminent danger, even though the original cause of the injury or threat has passed."

At the molecular level, cellular homeostasis or equilibrium is altered, creating an abnormal cellular response that leads to chronic disease. "When this happens during early child development," said Naviaux, "it causes autism and many other chronic childhood disorders."

Bonus Important Information:
ENDOTOXIN INDUCES BOTH OF THESE RESPONSES!!!!!!!!!!!!!!!!!!!!!

Friday, May 26, 2017

State of the Insanity

The GOP are now threatening the lives of some in my family.
ISIS has not done that in any real way.

Expert Opinion

As a person with a lifetime of experience with multiple types of hallucinations...
I can verify this "reality" is much, much worse.

Crazy is WAY better than this.

Wednesday, May 24, 2017

Substance over Style

Frankie goes Boom.

That's a man who knows what's truly precious.

Mad Men Indeed

Trump calls Kim Jong Un a ‘madman with nuclear weapons,’ according to transcript of Duterte call
(Duterte's) administration has overseen a brutal extrajudicial campaign that has resulted in the killings of thousands of suspected drug dealers.
Trump has not spoken out against that strategy, and in their call he praised Duterte for doing an “unbelievable job on the drug problem.”
“Many countries have the problem, we have the problem, but what a great job you are doing and I just wanted to call and tell you that,” Trump said, according to the transcript.
The most urgent drug problem in this country is caused by DOCTORS and PHARMAS handing out opiates to unsuspecting sick people.
See the vortex.

(edit, fixed link.  oops.)

Tuesday, May 23, 2017

Deviously Cruel

I'm pretty sure the horrifying budget cuts are a bargaining gambit.   He's staking out the extreme position.
Then they can act all magnanimous and pious when they generously allow completely disabled people to keep their caretakers and medications...
...But can still slash lots of other important reality based stuff like the NIH, CDC, EPA.
Because that's what's important.  That's what the corporate donors want.
Less oversight.
Less accountability.

Not My Imagination

Trump wasn’t always so linguistically challenged. What could explain the change?
STAT reviewed decades of Trump’s on-air interviews and compared them to Q&A sessions since his inauguration. The differences are striking and unmistakable.
My Hypothesis-
Tooth and Nasal infections (go figure)

Since the campaign, however, he has been getting less and less sleep and more and more memory problems
His sinus infection is affecting his entire head now, and he really can't think too well anymore.

update: Plus I think they're drugging him. Something like Benedryl maybe. He's very sleepy.
That's why he was grabbing Melania on the airplane stairs...

So Presidential

 “‘You can’t say what not to say,’ [a source close to H.R. McMaster] said of Trump, ‘because that will then be one of the first things he’ll say,” CNN reports.

Two days later
Trump says "I never mentioned the word or name Israel" to Russians

Sunday, May 21, 2017

Meanwhile in America

10 ways the GOP tried to sabotage Obamacare
Trump and Congressional Republicans have repeatedly said that the ACA is collapsing under its own weight, and that the exchanges are exploding. But while there is reason to be concerned about problems in the individual market, the story of Obamacare’s problems is not complete unless we take a look back over the last several years and look at all the ways Republican lawmakers, governors, and pundits – and now the Trump Administration – took steps to deliberately weaken the Affordable Care Act.

And now...
Trump reportedly wants to kill critical Obamacare subsidies, despite warnings health insurance premiums would spike

Extreme Antisocial Behavior

This qualifies for me.

$100 BILLION Arms Deal with SAUDI ARABIA.
(with $100 Million tip thrown in for bringing Veruca.)

The hypocrisy is staggering.
The spectacle is nauseating.

Friday, May 19, 2017

State of the Insanity

Thanks Rep Lieu.
Good Luck, World.





















Saudi Arabia isn't on the Ban List- they are going to give him the Royal Treatment.
Frankly, I hope Francis pope-slaps him upside the head.

This Seems to be the Goal

Thanks to Genetic Testing, Everyone Could Soon Have a Pre-Existing Condition

Oh Really...

Low cerebrospinal fluid Orexin levels in infants during SIDS risk period.

Hmmm, well-  low orexin levels are caused by infection and impaired breathing.
I suggest sucking the boogers out of kids noses before they sleep.
Oh, and SLEEPING ON AN INCLINE.

(this advice goes for adults with breathing problems too...)

No Divine Intervention Required

Scientists Propose New Theory for How Life on Earth Began

Glad I lived long enough to read this.  It's quite viable.

Thursday, May 18, 2017

Over the Edge












Listen Donny, you didn't think you were going to win so you didn't cover your ass.
And you left piles of shit everywhere for us to find and throw in your face.
Your denials are no longer plausible.
Fuck You, and Rupert, and Jeff Sessions too.

Wednesday, May 17, 2017

Speaking of the Redneck

Mmmmm.   I told you not to piss off the librarians...
We have a long history of being ordered about by smug white men.
We really like the black lady.

House Votes to Limit Powers of First Black Librarian of Congress

In a vote of 378 to 48, the House passed legislation to take power away from the current Librarian of Congress, Dr. Carla Hayden.
The legislation, H.R. 1695, was authored by House Judiciary Chairman Bob Goodlatte (D-Va.) and ranking member John Conyers (D-Mich.), would limit the powers of the librarian. It is expected to pass the Senate and be signed into law by President Trump.
The bill makes the head of the Copyright Office, the Register of Copyrights, a presidential appointment that would have to be confirmed by the Senate, rather than an appointment by the Librarian of Congress, as it has been since 1870. The bill also limits the position of Librarian of Congress to a ten-year term.
The previous Librarian of Congress, James Billington, served in the position for 28 years.
President Barack Obama appointed Hayden the 14th Librarian of Congress on February 24, 2016. She is the first African American to hold the position, as well as the first woman to be the Librarian of Congress, in the agency’s history. On March 23, legislation was introduced to block Hayden from appointing the next Register of Copyrights. That legislation passed the House on April 26.
Supporters of the bill argued that the legislation would help to modernize the Copyright Office and make it more accountable to Congress. Attempts to contact the office of Rep. John Conyers (D-Mich.) for details on why he authored H.R. 1695, were not answered.
“This bill serves no purpose other than to take power away from the Librarian of Congress and give it to powerful lobbyists, who will have a major say in who runs the Copyright Office,” wrote Michael Masnick on TechDirt.com on April 26. “It’s a bad bill, and it’s a gift to Hollywood.”
The entertainment industry pushed hard for the passage of H.R. 1695. It’s likely that the selection of the Librarian of Congress will be the focus of attention of the power of the entertainment lobby moving forward now that senators will play a role in confirmation.

No, this is a ginormous gift to Rupert.   Kisses darling! 

All the News

All the news Trump and Murdoch want them to see:

Tuesday, May 16, 2017

Mercy Me

I can't even comment on all the Science Shenanigans.  The prohibitions on research and publishing.  I can't read the articles.   The headlines alone give me full body tics...  I really don't want to weep on my computer....

Monday, May 15, 2017

We Are Now Here

The Sequence of Spiraling Symptoms:

Mania
Impulsiveness
Righteousness
Impulsiveness
Rage
Extreme Impulsiveness
Extreme Antisocial Behavior- We Are Now Here
Humiliation
Despair
Self-Destruction


It's Monday.
He goes to the Middle East on Friday.
Good Luck, World.

Sunday, May 14, 2017

Symptoms of Impaired Glucose Metabolism

Trump thinks that exercising too much uses up the body’s ‘finite’ energy

Sound familiar?

The Cognitive Slot Machine goes KaChing

Inside the West Wing, it became a running joke among some staffers that the answer to every question would be “Rosenstein,” referring to the deputy attorney general, Rod J. Rosenstein, who wrote a memo outlining a case for Comey’s ouster.

The Two Minutes Hate, from George Orwell's novel Nineteen Eighty-Four, is a daily period in which Party members of the society of Oceania must watch a film depicting the Party's enemies (notably "Goldstein" and his followers) and express their hatred for them for exactly two minutes.

Happy Mother's Day

U.S. Has The Worst Rate Of Maternal Deaths In The Developed World

And the Senate plans to cut funding to the most vulnerable women.
Maybe next week.

Photo of the Week



WWJD

One small step on the long road to sanity-

Pope Francis opens free laundromat for homeless

The Crux of the Biscuit

The painful truth about teeth
You can work full time but not have the money to fix your teeth – visible reminders of the divide between rich and poor.

But the absolutely gobsmacking truths about teeth are:
  1. If they are bad, the nerves are dead and there usually isn't any pain.   So you ignore them until you are septic.
  2. Too Much invasive dental treatment does just about as much damage to the immune system and brain as complete neglect.  It directly introduces oral microbes into the bloodstream.
Ultimately, this is the fundamental problem in medicine:  Separation of Dental and Body protocols.

Friday, May 12, 2017

Not Even Possible

Trump to TIME    "In a short period of time I understood everything there was to know about health care"

Feel the Gravity

See the Petards.


Thursday, May 11, 2017

See the Symptoms

Mania. Causes. Obsession.  

More thinking about Fewer things.  

Donald Trump After Hours

Zombie Shopping

Here are some Tee Shirts for the Resistance.
Wear you favorite Trump Tweet.

Created and sold by one of our favorite Gluten Free Narcos.

I am a big fan of this newfangled form of Petard Hoisting.

Wednesday, May 10, 2017

Some Good News


Can Cannabis Combat Age-Related Cognitive Decline?
The long-term administration of low-doses of the cannabinoid tetrahydrocannabinol (THC), the main psychoactive ingredient in marijuana, ameliorates age-related learning and memory deficits in mice, researchers have observed.
On the basis of this observation, the investigators plan to conduct a clinical trial to determine whether the finding applies to elderly individuals with and those without cognitive impairment, Andras Bilkei-Gorzo, PhD, of the Institute of Molecular Psychiatry, the University of Bonn, Germany, told Medscape Medical News.
Dr Bilkei-Gorzo and colleagues examined the effects of long-term, low-dose THC administration in young (2 months old), mature (12 months old), and old (18 months old) mice.
They found that THC treatment was associated with impaired behavioral performance on learning and memory tasks in young mice, but was associated with improved learning and memory in mature and old mice.
"THC treatment has practically the opposite effect in young and old animals," Dr Bilkei-Gorzo told Medscape Medical News.
"The same treatment rejuvenated old brains, whereas it made the young brains old. The reason of this phenomenon is that the activity of cannabinoid system declines in aging. In old animals, THC treatment restored the failing cannabinoid system activity, whereas it overactivated the normally functioning cannabinoid system in young animals," the researchers write.
Sounds like my kind of research...

We Are Here

The Sequence of Spiraling Symptoms:

Mania
Impulsiveness
Righteousness
Impulsiveness 
Rage 
Extreme Impulsiveness  -We Are Here
Extreme Antisocial Behavior
Humiliation
Despair
Self-Destruction

He had grown enraged by the Russia investigation, two advisers said, frustrated by his inability to control the mushrooming narrative around Russia. He repeatedly asked aides why the Russia investigation wouldn’t disappear and demanded they speak out for him. He would sometimes scream at television clips about the probe, one adviser said.
 Unless of course, the Republicans prop him up. Then we're all in the Mirror, forever.

Mission Accomplished Moment



















"'Oh, shut up, silly woman,' said the reptile with a grin. 'You knew damn well I was a snake before you took me in.'"

"Recursive Irony" Update

Why Ask Why Now?

Grand jury subpoenas issued in FBI's Russia investigation
Federal prosecutors have issued grand jury subpoenas to associates of former National Security Advisor Michael Flynn seeking business records, as part of the ongoing probe of Russian meddling in last year's election, according to people familiar with the matter. CNN learned of the subpoenas hours before President Donald Trump fired FBI director James Comey.

Tuesday, May 9, 2017

THIS IS WHY

Because suicide isn't unpredictable-  Mania and Righteousness are symptoms that come before Despair and Death.

Bearing Arms editor Bob Owens dead from apparent self-inflicted gunshot wound
Bob Owens, editor of the popular pro-gun blog BearingArms.com, died Monday in an apparent suicide, authorities say.
Owens was found around 11 a.m. near a stop sign outside his subdivision in Fuquay-Varina, N.C., a town southwest of Raleigh. A gun was located nearby, according to the Fuquay-Varina Police Department.
An autopsy to determine the cause of death is still pending, but police said the gunshot wound was “possibly … self-inflicted.”
Shortly before Owens’s death, he apparently wrote a chilling message on Facebook: “In the end, it turns out that I’m not strong. I’m a coward, and selfish son of a b‑‑‑‑. I’m sorry.”

Friday, May 5, 2017

For the Record

I would be willing to let men write ALL the laws-

If the Supreme Court was ONLY women.

Devil's Advocate

Maybe the people who don't believe in Evolution should be the ones denied health care.

I mean really, if you don't believe in the basic facts of biological science, why do you use the products and services?

Revenge of the Microbes

There are diseases hidden in ice, and they are waking up

Long-dormant bacteria and viruses, trapped in ice and permafrost for centuries, are reviving as Earth's climate warms

Buckle Up, Gen X

It's going to get real advantageous for companies to start laying off people over fifty.
You know, the ones who have all those documented medical conditions.

Fascinating

Erectile Dysfunction is not considered a pre-existing condition, although it is clearly caused by long-term progressive pathology from an unhealthy lifestyle....like drinking alcohol (or fructose) and sitting on your ass a lot...





Thursday, May 4, 2017

Dear Elderly People

Congratulations.  You are halfway to destroying what's left of my decimated generation.
And everyone younger than us too.

Please, do enjoy your Medicare and Social Security and Righteous Certainty.  While you can.

(While you still receive your benefits, do consider that the AHCA strips out the Medicaid funding that pays for in-home nursing care or a nursing home.  If it passes the Senate, I hope you have alternate plans for someone to feed your face and wipe your ass.  Don't count on us to still be around.)

This will haunt Her

Martha McSally stood up in GOP conference meeting and said "Let's get this fucking thing done". Yes, direct quote — per members and aides.

This is my Representative. She's unwavering in her desire to kill sick people in Tucson.


There is no CBO score. These people are hypocritical lying cheaters. Period.

Vicious Circles

All his teeth are fake.
And he drinks Coca-Cola all day long.

As Cruel As It Gets

Ladies and Gentlemen- Republican Squad Goals:
Under the GOP's health plan, Sexual Assault and Domestic Abuse could be considered preexisting conditions.

And not just for Obamacare.   Private and Employer insurance too.

Sheer Unmitigated Evil.    Codified by Congress.

JUST IN: ObamaCare repeal bill contains exemption for members of Congress and their staffs

State of the Insanity

@StephenKing

That this guy has his finger on the nuclear trigger is worse than any horror story I ever wrote.

Tuesday, May 2, 2017