The receptors, or sensors, on cells are called Toll-like receptors (TLRs), and the Nobel Prize was awarded last year for discoveries that showed they initiate the swift innate immune response to infections. But the inflammation they trigger can also be harmful. In mice it has been shown that two TLRs -- TLR2 AND TLR4 -- are important in the development of both diabetes and heart disease.Okay, here we go again-
This is a mechanism not a trigger.
The receptors and the cytokines are involved in immune response to infections.
Infections are already documented to cause heart disease and obesity.
Cause and effect. See how that works?
