Jet Lagged

Lack of sleep can seriously affect metabolism

The changes were huge: After sleeping four hours a night for four nights, the subjects' whole-body insulin response decreased by an average of 16%, and the fat cells' insulin response decreased by 30%. The researchers say that those levels are akin to the levels seen in diabetics or the obese. And when the team looked at the biochemical markers of an insulin response in the fat cells they removed, they found it took three times as much insulin to cause a normal response after four nights of limited sleep.