They suggest that loneliness may affect cognition and memory as a result of loss of regular use, or that loneliness could itself be a sign of emerging dementia, and either be a behavioural reaction to impaired cognition or a marker of undetected cellular changes in the brain.I'm going with the second option.
I'm not real fond of this experiment (lonely is a subjective definition), but it does confirm my experience.
I have always felt alone. It was unbearable when I was young.
It's ironic how the desperation makes one less likely to have friends.
And the cumulative neurological effect is to be unable to cope with people at all.