Deep brain stimulation (DBS) in a precise region of the brain appears to reduce caloric intake and prompt weight loss in obese animal models, according to a new study led by researchers at the University of Pennsylvania. The study, reported in the Journal of Neuroscience, reinforces the involvement of dopamine deficits in increasing obesity-related behaviors such as binge eating, and demonstrates that DBS can reverse this response via activation of the dopamine type-2 receptor.Ooh, brain surgery will make doctors even more money than stomach surgery.
Funny thing though- amphetamines- which depressed and fat people seem to find very effective in easing their symptoms- actually reduce D2 receptor activity.