Twelve overweight or obese men consumed test meals designed as milkshakes with the same calories, taste and sweetness. The two milkshakes were essentially the same; the only difference was that one contained rapidly digesting (high-glycemic index) carbohydrates and the other slowly digesting (low-glycemic index) carbohydrates.Post-prandial hypoglycemia.
After participants consumed the high-glycemic index milkshake, they experienced an initial surge in blood sugar levels, followed by sharp crash four hours later.
This decrease in blood glucose was associated with excessive hunger and intense activation of the nucleus accumbens, a critical brain region involved in addictive behaviors.
Prior studies of food addiction have compared patient reactions to drastically different types of foods, such as high-calorie cheesecake versus boiled vegetables.
Another novel aspect of this study is how a specific dietary factor that is distinct from calories or sweetness, could alter brain function and promote overeating.
"These findings suggest that limiting high-glycemic index carbohydrates like white bread and potatoes could help obese individuals reduce cravings and control the urge to overeat," says Ludwig.
Sounds like they were orexin deficient to me.
