Dietary saturated fat reduces alcoholic hepatotoxicity in rats by altering fatty acid metabolism and membrane composition.
As dietary saturated fat content increased, all measures of hepatic pathology and oxidative stress were progressively reduced, including steatosis . Thus, saturated fat protected rats from alcoholic liver disease in a dose-responsive fashion.
Seriously, this research stuff is bad for my serenity.Dietary fat is an important cofactor in alcohol-associated liver injury. We demonstrate that USF (corn oil/linoleic acid) by itself results in dysregulation of intestinal tight juncion integrity leading to increased gut permeability, and alcohol further exacerbates these alterations.
I think I'm going to vomit.