Surfing the Collagen Matrix

The Endocrine Society has renamed PCOS to PMOS.   Apparently this reclassification took 10 years.  

PCOS is a condition which causes women's eggs to have thickened and malformed collagen wrappers, resulting in problems with ovulation and fertility.   It is also frequently comorbid with insulin resistance or diabetes....

The enzyme LOX, which is crucial for cross-linking collagen, is frequently overexpressed in PCOS

P. gingivalis infection significantly upregulates host LOX-1 expression in endothelial cells and macrophages.

Porphyromonas gingivalis may interfere with conception in women

I think the way this works is:   The bacteria infect the uterine area.   They produce gingipains which degrade the collagen and stimulate overproduction.

-------------------

While I was suppressing my ovaries, my sister was having her dozens of follicles scraped every year.  She actually ended up with the most interesting complication.... Twins who were conceived two weeks apart.   True story.

Rage Quitting is a Symptom

Holy Hyperactive Habenula Batman.

LOL.   Keep up the pressure, people.

Although I do prefer just leaving without a word, I did once say  "Fuck You Craig, I Quit" to a boss before walking out the door.   I don't regret it.   Craig was a spoiled rotten sociopath.  

How this ends

 DOGE wanted to declare 2.7 million people dead at Social Security: whistleblower

The Department of Homeland Security initially asked the Social Security Administration to mark about 6,000 living people as dead, and those people were added to the death file, according to the latest complaint. They were later removed from that database, the complaint said.

 THIS IS A LIE.    They are activists and they have not been removed.  One of them is a friend of mine.  White. Male, American Citizen.   He cannot even get anyone at SSI to admit he's alive.   It's a fucking nightmare.   He's a cyber zombie.

I'm pretty sure this is their goal for all of us.

State of the Insanity

DOJ Declares Trump Has Right to Bulldoze Statue of Liberty

Now I'm assuming he wants to.   Well, that tracks.   Fuck your tired and poor...

Correlation Games

 New AI body map reveals obesity’s hidden attack on facial nerves

A powerful new AI body-mapping system revealed that obesity may quietly damage facial nerves — not just metabolism.

They are stealing ALL the data Right the Fuck Now

Trump.rx is a front for medical data theft.    And that's just the beginning....

 I found a second vote.gov — and it's registered to the White House

And now.....

RFK Jr. seeks to peek at Americans’ medical records for clues on autism and vaccines

Good Morning Orwell

Rep. Lieu showed him the videos

"Secretary Rubio, have you been at more than one meeting where President Trump has fallen asleep?" the Democratic lawmaker asked during Wednesday's House Foreign Affairs Committee hearing.

Rubio said that was false.
"I've never seen him fall asleep," he said. "On the contrary, the guy doesn't sleep, which is a big problem," adding that Trump has called him in the early morning hours.
"Secretary Rubio, I'm going to show you in a moment a video that shows you just lied to Congress."
A video of last month's Cabinet meeting then plays. Trump is again shown sleeping, while Rubio is speaking about wartime matters.
"You are literally talking about issues of war and peace and Donald Trump is sleeping right next to you," Lieu said, repeating that Rubio was lying to Congress.
Rubio again said Trump wasn't asleep, saying that the videos being shown in the hearing aren't showing the president is dozing off.

“The Party told you to reject the evidence of your eyes and ears. It was their final, most essential command.”

― George Orwell, 1984

Unbabied you say

 

Silver Alert

Last seen sleeping in public.  Perfectly.

Another week missing at the end of the month.

Thanks for the evidence

Scientists found the hidden switch fueling Alzheimer’s brain inflammation

Scientists at Scripps Research have uncovered a molecular “switch” that appears to fuel the damaging brain inflammation seen in Alzheimer’s disease. They found that a protein called STING becomes chemically altered in a way that keeps the brain’s immune system stuck in overdrive, harming the connections between nerve cells.

Porphyromonas gingivalis induces an inflammatory response via the cGAS-STING signaling pathway in a periodontitis mouse model

Our results demonstrate that the cGAS-STING signaling pathway may be one of the key mechanisms crucial for the P. gingivalis-induced inflammatory response that leads to chronic periodontitis.

Proud Boy

ICYMI:   Greg Bovino had a playdate with his "just friends".

80 years old

Has anyone ever wanted to go to his birthday parties?

 Cancel it', Trump says after artists drop out of US Freedom 250 festival

As I was saying

Scientists discover why Alzheimer’s risk hits women so much harder

No they didn't.   

Most of this is caused by the difference in men's and women's immune response.   

Their  list of "risk factors" are merely other (very profitable) manifestations of the infections that cause Alzheimer's. 

Men have suppressed immune systems due to anabolic steroids like testosterone.  

Women have increased immune responses triggered by estrogen.  

Since Alzheimer's is caused by a surplus of immune response molecules clogging up the brain...women will have more pathology.  The same imbalance applies to narcolepsy patients.

(I suppressed my ovaries with progesterone birth control from the time I was 16 until I was 50.   I participated in the clinical trials for all the forms:  pills, shots, and implants.  Looking back, it's surely one of the reasons I'm still alive.   Why I wasn't institutionalized.  Why I didn't just wither and die when I was 42 and the dementia set in.)

His Holy Grail

Here's the plan

Oh my.    Putin and Xi know this.   They're going to strike during a Cabinet Meeting.

Excellent Documentation of the Obvious

Man Didn’t Know How Weird Men Were Until He Changed His Profile To A Woman’s Picture On TikTok

On a tangent

I like this topic. 

The Evolution of Throwing

Origins of human throwing unlocked

I only ever throw things when I am really really pissed off.  I have never wanted to throw or catch a ball or anything else for fun.

My nephews started obsessively throwing rocks overhand when they were 2.

It's something I think about sometimes.  Ballistics. Strategy.   Long distance domination.  

And why men think about it all the time....

Yeah

 March 2021

Uh huh

 Sept 11, 2025.     Just sayin.

How about that

Mexico launches Universal Health Service registration, starting with elderly

I find it quite noteworthy that a google search does not find any major news outlets reporting this story.   

There is no bottom

Stop calling it a Ballroom just because he does.   Stop the construction immediately.

It's a Big Baby Bunker.   He has no plan to give up the keys to the White House.  That's why it's his priority.   He hasn't got much time to get it done.

It's got a restaurant and a hospital and a military command center so he can lay in bed, get his burgers and drugs, and shit himself while streaming the destruction of America life-size on massive TV screens.  

He's going to lock himself in and gather his human shields around the building.  If I were a gambler, I'd put money on that.  That's his kind of fun.

Cha Ching

I know his secret.

The goddess Nemesis is on her game.  She's going to take his mouth and face.  His very favorite things... (she already has the mushroom)

Here we go

The Functional Roles of Curcumin on Astrocytes in Neurodegenerative Diseases

have fun.   I'm still reading...

Mansplaining

Why women put up with more than they should  short video

I love her chirp after "plan ahead".   You don't say!  No kidding? <eyerolls>

It's also why we cooperate with eachother...

I would like to reframe that patronizing title:  Why men remain babies and believe their own bullshit. 

Article Roundup

Porphyromonas gingivalis promotes neuroinflammation and neuronal loss associated with dysfunction of the brain barrier

Curcumin attenuates cell migration in human ovarian cancer cells

Severe COVID or flu may raise lung cancer risk years later

Sepsis is linked to nearly one in five pediatric hospital deaths in the US

Scientists just discovered what coffee is really doing to your gut and brain

New study debunks the biggest fear about yo-yo dieting

A hidden map in your nose could explain how smell works

People who underwent root canal treatment experienced better blood sugar control 

Alzheimer’s drugs may not work and could raise brain risks
A major review finds Alzheimer’s drugs that remove amyloid may do little good- and could carry hidden risks.

Scientists reversed memory loss by recharging the brain’s tiny engines
more mitochondrial science soon...

What I Learned About Billionaires at Jeff Bezos’s Private Retreat
For the richest men on Earth, everything is free and nothing matters.

Sea shanties actually help people work together better