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As I was saying...            

Women with Polycystic Ovary Syndrome (PCOS) face an elevated risk of postpartum depression, with studies showing a roughly 45% to 50% higher likelihood compared to women without PCOS.

Polycystic ovary syndrome and postpartum depression symptoms: a population-based cohort study

A fine specimen

 

Another vortex in the matrix

Another cruel feedback loop:

Marfan syndrome is a genetic condition that damages the body's connective tissue, which supports bones, muscles, organs, and blood vessels.  It is caused by a mutation in the FBN1 gene that disrupts the production of a protein called fibrillin-1. Human fibrillin-1 is a critical molecule that forms microfibrils, providing structural scaffolding for elastic fibers throughout connective tissues all over the body.  This results in skeletal and cardiovascular changes, including long limbs, chest wall deformities and weak aortic walls.  It also degrades the gingival tissues and periodontal ligaments.   Marfan patients have an increased incidence of periodontal disease than contol subjects.

Porphyromonas gingivalis produces Gingipains, molecules which degrade host connective tissue  proteins. While their primary targets are fibronectin and collagens, they also target the surrounding microfibrillar network including fibrillin structures, leading directly to tissue destruction, impaired wound healing, and bone loss.  P. gingivalis travels all over the body and is a documented trigger of atherosclerosis.

Periodontal condition in growing subjects with Marfan Syndrome: a case-control study

Oral health in patients with Marfan syndrome

Periodontitis May Deteriorate Aortic Sinus Dilatation in Marfan Syndrome Patients

Oral Health Status in Marfan Syndrome: A Systematic Review and Meta-Analysis of 353 Cases

Impulse Control Problems

 Donald Trump: ‘I Have Some Very Severe Problems’

Oh Really

“But remember, I’m the only one who took the test. You know, the aptitude test or whatever the hell they call it. I took it— when I did— every time I do a physical— I take a mental test. And I’ve aced it. WHERE’S MY DOCTOR? Is he around, I travel with more doctors than any human. If people get sick in the audience, they don’t— do— they leave him alone. You know what they call him? Collateral damage.”

Insanity Squared

Tiger Victim Identified as Child Actor Struggling With ‘Significant Mental Illness’

World Appalled By Trump Parodying Fatal Tiger Mauling Video

Behold the power of microbes.

State of the Insanity

Bribes and Circuses.

US to livestream Army firing squad execution of Fort Hood shooter

Piggy and the Secretary of the Flies...

Emphysema in the House

COPD enters the vortex.

Porphyromonas gingivalis and Scardovia wiggsiae promote neutrophil-induced lung epithelial cell apoptosis and Emphysema

Edit:

Daily Curcumin Reduced Inflammatory Markers, Improved Cough, and Dyspnea in COPD Patients

Every accusation is a confession

Trump boasts about his mobility at rally: ‘I can go ramp, I can go stair’

Sorry about your prostate...

jk.

Extremism is the product of the pathology

Palantir cofounder Peter Thiel: 

"If you're evil, you're not bad. You're actually maybe kind of good."

Malevolence and Incompetence

 Tennessee governor halts executions after Christa Pike survives lethal injection attempt

How many levels of horrific is this story...

A few things

America had wiped out measles. Now babies are infected at birth.

Dietary Polyphenols as Therapeutic Intervention for Alzheimer’s Disease: A Mechanistic Insight      Curcumin is a polyphenol.

Just 5 Infections Responsible For More Than 2 Million New Cancer Cases Annually

So close.   I was really hoping....

My algorithm finally gets it right. LOL.

How did Ancient Egyptians Sleep?

Stephen Dalton's Humorously Dull History for Sleep

More of the Same

 Trump’s Drug Pricing Deals Favor Big Pharma Over Patients

Article Roundup

 Tooth count may predict survival after pancreatic cancer surgery

Pancreatic cancer patients with at least 21 natural teeth survived nearly two years longer after surgery than those with fewer teeth in a study of 339 people. Researchers suspect tooth loss may reflect decades of inflammation, frailty, nutrition, and other factors tied to the body’s overall resilience.

No    It's chronic infection.

Porphyromonas gingivalis‑derived lipopolysaccharide inhibits brown adipocyte differentiation 

This is the reason we do not exhibit fevers and are always cold.

Immune cells flood into the aging brain

COVID-19 awakens dormant viruses — and one is linked to long COVID

The bacteria that make cheese taste so good may also benefit your gut

Yay!

Your gut microbiome may be more contagious than scientists thought

Caffeine may flip an ancient cellular switch linked to slower aging
Caffeine may help cells age more slowly by switching on a powerful energy and stress-response system.

Herpes rewires energy metabolism in human neurons, imaging study reveals

Trauma-induced changes in the brain differ significantly between males and females

More Irony

 FDA Announces Ongoing Recall of Hand Soap in 15 States Due to Potential “Bacterial Contamination”

The GOP is Killing Us For Money

Angry Male Vet is a good man.

Everywhere. Always.

World’s oldest evidence of habitual drug use found in 25,000-year-old teeth in Indonesia

Ice age hunter-gatherers on an Indonesian island regularly sucked betel nuts to ease tooth pain, according to a new study. 

This is Insane

Clorox Recalls Pine-Sol and Clorox  Cleaners Due to Risk of Exposure to Bacteria

Clorox Recalls 6.3 Million Bottles of Mistolin and Lestoil Cleaners Over Bacteria Risk to Vulnerable Users

Big red flag

This is a symptom of bacteremia:

One more time

 GOP Senator, 73, Shows Worrying Health Condition She Covered Up

Essential Tremor is a problem.  4 men in my family have/had it.  Trust me, it gets worse.  If you get old enough it morphs into Parkinsons.  

She's getting much worse.

New Song of the Day

 The Brain Song – “Weird Al” Yankovic

But of course

Natalie is an Emercency Medical Technician in Ivanka drag.  The perfect babysitter.  I'm beginning to wonder if Melania hired her...

Oh Shit!  Literally.   I just realized he's a noncompliant celiac.   That explains the diapers.

For Hayden and Lindsay and moms everywhere

Post-Partum Depression/Psychosis is probably caused by persistent bacteremia in the birth canal.  

Pregnancy increases periodontal disease

Childbirth causes all kinds of tissue trauma.

Childbirth trauma is common and increases risk for postpartum depression

Antidepressants promote the spread of antibiotic resistance