The total is now seven. That doesn't include the four wisdom teeth that actually needed to go (much sooner than they did).
Wednesday, March 11, 2026
Off to the dentist
To have another tooth removed. The third crown has failed. Another tooth my dentists destroyed with inappropriate treatment.
Correlation Games
Steven Cheung Trump political advisor, White House communications director.
Steve Bannon- former White House Chief Strategist, advisor to Jeffrey Epstein.
Stephen Miller White House deputy chief of staff for policy and homeland security advisor.
Monday, March 9, 2026
Tick Tick Tick Tick Tick
60 Minutes- Havana Syndrome investigation is "a massive CIA cover-up"
For years, the U.S. government has doubted the stories of those suffering from AHI, commonly called Havana Syndrome. Now, victims hope that reports of a newly discovered weapon will finally vindicate them.
You dispicable men have been dreaming of this kind of silent, invisible power forever. Fuck all y'all.
Boys will be Boys
Russia, China, and Iran have joined forces.
Bibi and Trump want to Nuke Iran. More than anything. Neither one of those demented zombies will ever stop thinking about it now.
Trump thinks he can get their Uranium. What he will get: our most elite commandos slaughtered.
Hegseth and Miller will shrug.
And Putin will dance.
Sunday, March 8, 2026
As I was saying
A quote from me:
P. gingivalis highly activates the Habenula in the brain. The habenula causes panic attacks and major depressive disorder. Avoidance behavior. Fleeing from aversive stimuli.
That part of the brain tells you if it thinks your decisions are wrong. An overactive habenula makes you think your decisions are always wrong. Your behavior is wrong. Everything you do is wrong. Everything you ever have done is wrong. Everything you ever will do will be wrong. Acute dysfunction creates the feeling of absolute futility and is the source of suicidality.
Yeah, been there, done that. My entire life. It really makes being told you’ve made a mistake an excruciating experience. It makes you hate and avoid authority. You blame them for causing your pain.
It’s almost impossible to admit a mistake. It feels like the end of the world. We’ll do anything to avoid it.
That explains a whole lot of things I see every day.
This too:
Saturday, March 7, 2026
Friday, March 6, 2026
25th Please
Kristi Noem is out.
ICE can't wear masks.
The department of Justice has released the 302 files about nasty Trump.
Somebody has decided it's time for him to go.
Let's see how long it takes.
Unemployment is insane. Gas prices are skyrocketing. The stock market is plummeting.
Today would be good.
Trump tells CNN Cuba is soon going to fall: ‘I’m going to put Marco over there’
Thursday, March 5, 2026
Make it stop
He forgot where his father was born. Twice. His orexin levels are so low he can barely move his mouth muscles. He can barely mumble. He's talking in his sleep.
He's got Dementia and Tourettes, Active Herpes, dental problems and is clearly on drugs.
His mouth is now moving indepedently of his brain. Which Cannot Recall Proper Names or Places or Numbers. A DEFINITE SIGN OF ASTROCYTE ACTIVATION.
His mouth is a Robot Mad Lib. He fills in the gaps with similar words. Like an AI text generator. He's babbling nonsense.
Somebody needs to hospitalize him. Amyloid test him immediately.
He's the single greatest danger on the planet.
Our military is strung out all over the world.
We are losing people and infrastructure every day.
NATO is fractured.
And Putin is going to die happy.
Dear young people- save this clip. You will need it to teach your children history in the future. They won't believe you.
Wednesday, March 4, 2026
Monday, March 2, 2026
He has active herpes
That is shingles on his neck. Herpes Zoster. That's a strong contributor to Alzheimer's.
I had shingles on the top of my head It's really painful. It clogs up your brain. I couldn't function for 3 weeks.
It seems probable that whatever they are infusing into his hand has lowered his immune response. Microbial Whak-a-Mole. My old friend....
Diagonal Earlobe Crease, a Marker of Coronary Artery Disease
In the meantime
Excerpts from:
Sexual dimorphism in bacterial infections
Periodontal infections show sexual dimorphism, for instance, men are more susceptible than women to develop periodontitis, which as other infections are mainly attributed to the elevated production of pro-inflammatory cytokines in response to differential gene regulation through the action of sex steroid hormones. Interestingly, chronic periodontal inflammation is considered a cause of endothelial dysfunction by inducing reactive oxygen species production, that in turn contributes to the development of cardiovascular diseases, which are more frequent in men than in women.
Testosterone generally functions as a suppressor at early stages of infection, but as an activator during the late response to infection, as it occurs during sepsis; whereas, estradiol acts as an activator, and progesterone functions as an immunosuppressive agent, mainly during pregnancy.
In general, males are more susceptible to gastrointestinal and respiratory bacterial diseases and sepsis, while females are more susceptible to genitourinary tract bacterial infections. However, these incidences depend on the population evaluated, animal model and the bacterial species. Female protection against bacterial infections and the associated complications is assumed to be due to the pro-inflammatory effect of estradiol, while male susceptibility to those infections is associated with the testosterone-mediated immune suppression.
Certain gastrointestinal infections are more recurrent and severe in men than in women. This sexual dimorphism can be explained in part because of behavioral differences during hygiene and eating practices, such as handwashing before food handling and eating, storage, refrigeration, and defrosting practices, and tendency of men to eat undercooked or raw food, as well as to ingest roadside food .
During gastrointestinal injury, males produce predominantly pro-inflammatory cytokines, as compared with females whose intestine produce anti-inflammatory factors. in turn, the inflammatory response in males leads to perforation and cell necrosis at the site of infection.
Infections caused by Helicobacter pylori affect predominantly males, and its outcomes, such as gastritis, peptic ulcer, and gastric cancer, are also more frequent in males
It has been suggested that male sex is a frequent risk factor and a predictor of worse outcome for most of the respiratory tract infections, with exception of some upper respiratory tract infections (sinusitis, tonsillitis, and otitis externa) that are more frequently found in females.
The incidence of community-acquired pneumonia is higher in men than in women, and this incidence increases by age, especially in infections with Streptococcus pneumoniae, Streptococcus pyogenes, Chlamydophila pneumonia, and Legionella pneumophila.
In fact, male gender is considered as one of the four risk factors associated with the development of sepsis in general surgical and post-traumatic patients, with a hospital mortality rate of 70% in male and 26% in female patients.
One of the most used models to simulate bacteremia is LPS injection into bloodstream, which is known as experimental endotoxemia. Although there are controversies about the mechanisms involved in the sexual dimorphism of LPS response, it is accepted that males are more affected than females in LPS-induced endotoxemia.
A large number of genes related to immune functions are located on the X chromosome, X-linked mosaicism allows women to respond with a more expanded immune repertoire as compared with men.
Among other diseases that display a sex-based predominance are urinary tract infections (UTIs), which are present in females more often than in males. UTIs in women occur more frequently than in men due to anatomical and physiological differences; for example, the urethra is shorter than that of men, and the distance between the anus and urethral meatus is also shorter in women. Additionally, the perimeatal region has less humidity in men than in women and prostatic secretions show antibacterial activity; therefore, the probability of bacterial colonization and development of infection is lower in men.
(I believe this is why women get more upper respiratory infections. Our heads and necks and mouths and sinuses are smaller)
Sexually transmitted infections also have female predominance; as it is the case of infections of the genital tract caused by Chlamydia and and Neisseria gonorrhoeae.
Aging and menopause also influence the immune system function, increasing the predisposition to infections. During menopause, there is a significant reduction in sex steroid hormone synthesis with a concomitant decrease in immune cell levels and their functional capacity.
Uh-huh
Ndiaga Diagne was identified as the gunman who killed two people and injured 14 others during a mass shooting at a bar in Austin, Texas.
Yeah, he's been exhibiting aggressive behavior for a long time.
He apparently started taking diet drugs. Considering the psychosis, I'd guess amphetemines.
Sunday, March 1, 2026
It's a mystery
‘Boy kibble’: why are young men turning to dog food for meal inspiration?
Digestive and motivational disorders caused by terrible medical advice?
Saturday, February 28, 2026
We will not forget
Trump and Israel are still all over the Epstein Files. I think we should change the slogan to "Wag the Dick".
Article Roundup
Common pneumonia bacterium may fuel Alzheimer’s disease
Chlamydia pneumoniae can invade the retina and brain, where it sparks inflammation, nerve cell death, and the buildup of amyloid-beta—the hallmark protein linked to Alzheimer’s
yeah, in my day this was called bingeing and purging.
Compared with earlier generations, they report more loneliness and depression, along with weaker physical strength and declining memory.
red flag red flag red flag!
In people with Crohn's, the researchers found two bacteria, E. coli and Serratia marcescens, move "in lock step" with the fungus Candida tropicalis, working to produce a biofilm that prompts inflammation typical of Crohn's disease.
Much speculation and no mention of orexin
(My belief: Mesolithic women are the prehistoric geniuses who figured out how to brew alcohol.)
Friday, February 27, 2026
Some moments in the Matrix
Here's my lastest rambling screed.
Auntie Zombie adds some thoughts
It really has been a glaring omission that I didn't have anything about sleep or eating disorders. Sorry about that.
I still have plans for a discussion on Sexual dimorphism in immune responses. I wish someone would write that for me....
In the meantime:
High-Testosterone Men Have the Weakest Immune Responses
Thursday, February 26, 2026
Good Article
New review. Some chemistry jargon, but the main points are worth reading. Has a section on Astrocytes, oh my.
Porphyromonas gingivalis: a potential trigger of neurodegenerative disease
Cortisol Exposure leads to Astrocyte dysfunction in Major Depression
Yeah. That's what this experiment showed.
Using the 7-day exposure paradigm, we studied the specific impact of chronic cortisol exposure in MDD patient-derived astrocytes with whole transcriptome analyses. We discovered uniquely disrupted pathways in MDD astrocytes exposed to chronic cortisol. Genes involved in GPCR ligand binding, ion transport, and synaptic transmission were uniquely affected by chronic stress in MDD astrocytes, notably the serotonin receptor HTR1B, the neurotrophic factor GDNF, and glutamate receptors GRM1 and GRM8. We have generated a novel in vitro chronic stress-like paradigm and provide evidence for the unique regulation of astrocyte genes in MDD.
Another 20-something shooter
His family has obvious dental and metabolic problems. Let's guess infected 3rd molar for him. I would check their APOE status too. I used to look just like mom. I see that lady everywhere. There were three of us in my library school classes. And we all studied medical indexing not literature. I wondered why for about 15 years.
Wednesday, February 18, 2026
Everything Old is New Again
Rerun.
On the topic of Cults
Since everyone has infections, everyone is susceptible to the symptoms.
Symptoms like depression and anxiety.
Religion and Cults and Psychs use this to manipulate you. They get you in the door using that fact. They literally seek people out who are in crisis to exploit these symptoms.
Then they start wasting your time. Taking your money. And making your symptoms worse.
They control your food and sleep and information. They exhaust you.
They get you to confess your mistakes. They learn the triggers of your habenula so they can make you feel bad at will. Coerce you to comply.
When you do, then they give you positive social reinforcement to make you think your problem has been solved.
It hasn’t. You’re still sick and your astrocytes are fossilizing in your brain. All of your colleagues are infected too. Your ability to think is diminishing.
The longer you stay, the less ability you have to leave.
Symptoms like depression and anxiety.
Religion and Cults and Psychs use this to manipulate you. They get you in the door using that fact. They literally seek people out who are in crisis to exploit these symptoms.
Then they start wasting your time. Taking your money. And making your symptoms worse.
They control your food and sleep and information. They exhaust you.
They get you to confess your mistakes. They learn the triggers of your habenula so they can make you feel bad at will. Coerce you to comply.
When you do, then they give you positive social reinforcement to make you think your problem has been solved.
It hasn’t. You’re still sick and your astrocytes are fossilizing in your brain. All of your colleagues are infected too. Your ability to think is diminishing.
The longer you stay, the less ability you have to leave.
Tuesday, February 17, 2026
Cha Ching Ching Ching!
Brain inflammation may be driving compulsive behavior
For years, compulsive behaviors have been viewed as bad habits stuck on autopilot. But new research in rats found the opposite: inflammation in a key decision-making brain region actually made behavior more deliberate, not more automatic. The change was linked to astrocytes, brain support cells that multiplied and disrupted nearby circuits. The discovery hints that some compulsive behaviors may arise from excessive, misdirected control rather than a loss of it.
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