The researchers found that regular use of the NSAID naproxen, the active ingredient in medications such as Aleve, is associated with a 10 percent increased risk of heart attack, stroke and death in postmenopausal women, said UF cardiologist Dr. Anthony Bavry, the study's lead author. Regular use was defined as at least twice per week for the previous two weeks.Actually- these side effects were documented before approval.
Peter Goetzche documented that extensively in his book.
