Thursday, August 27, 2020

Article Roundup

Dual orexin and MCH neuron-ablated mice display severe sleep attacks and cataplexy.
Well hey there, isn't that fascinating...

Orexins modulate membrane excitability in rat trigeminal motoneurons
This means orexin improves facial movement.

Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders
Interesting. didn't work on my sleepiness though...

The role of suvorexant in the prevention of delirium during acute hospitalization
Based on the reviewed literature, suvorexant has shown positive outcomes in the prevention of delirium during an acute hospitalization.

A clue as to why it's so hard to wake up on a cold winter's morning

Sleep and orexin: A new paradigm for understanding behavioural-variant frontotemporal dementia?

Hangover drug shows wider benefits in USC research
Researchers found it activates a cascade of mechanisms that erase alcohol from the body very quickly,

How does the brain link events to form a memory? Study reveals unexpected mental processes

Neuroscientists find memory cells that help us interpret new situations

Right under your nose: A more convenient way to diagnose Alzheimer's disease
Certain proteins in nasal discharge can indicate the onset and progression of Alzheimer's, providing an avenue for early detection

How ApoE4 endangers the brain
ApoE4 prevents the recycling of sortilin, which removes beta amyloid.

Aging memories may not be 'worse', just 'different'

Trouble remembering details of social interactions seen in all phases of schizophrenia

Inflammatory bowel disease linked to doubling in dementia risk

 New gut-brain link: How gut mucus could help treat brain disorders

Porphyromonas gingivalis and digestive system cancers 

Greedy for glucose: Cancer cells rely on a primeval energy-producing pathway to proliferate and spread

Researchers discover the microbiome's role in attacking cancerous tumors

Study focuses on low-carb, high-fat diet effect on older populations
We also found significant improvements in the overall lipid profile that would reflect decreased risk of cardiovascular disease," Goss said. "Further, insulin sensitivity improved in response to the very low-carbohydrate diet reflecting reduced risk of Type 2 diabetes. Overall, we observed improvements in body composition, fat distribution and metabolic health in response to an eight-week, very low-carbohydrate diet."

Calculating the reduction in worldwide deaths from liver cancer if the whole world drank more coffee
A team of researchers affiliated with multiple institutions across Australia has found that if everyone in the world drank at least two cups of coffee every day, the world would see hundreds of thousands fewer deaths from liver cancer. In their paper the group describes calculating their numbers and explains why they believe governments should begin encouraging people to drink more coffee.

Coffee stains inspire optimal printing technique for electronics

 The hair-raising reason for goosebumps
The same cell types that cause goosebumps are responsible for controlling hair growth

Are Braces a Scam?
Heidi says yes.   Pretty teeth do not a healthy mouth make.


More underwater coastal archaeology:
Is There A Sunken Civilisation In The Black Sea? (video)
Why this is important: because the time period that humans were first building permanent dwellings was before some major glacial flooding and a large sea level rise. Like now, prehistoric people chose to live near sources of water. Therefore most of the evidence of our first societies is now submerged.