Wednesday, August 6, 2025

Free your mind

New hope for Alzheimer’s: lithium supplement reverses memory loss in mice

The clues added up. The authors found that lithium levels were lower in parts of the human brain affected by Alzheimer’s disease than in unaffected regions. The team also discovered that in people with mild cognitive impairment, a precursor to Alzheimer’s, brain lithium is tied up in amyloid plaques, leaving less available for essential brain functions. This lithium withdrawal “became more severe as the disease progressed”, says Yankner.

Isn't that interesting, a product of the brain's immune response- Beta Amyloid- actually binds to and sequesters an antimicrobial molecule.   Go figure.

This is not the cause of the problem, it is an effect.


Antibacterial Evaluation of Lithium-Loaded Nanofibrous Poly(L-Lactic Acid) Membranes Fabricated via an Electrospinning Strategy

Adhesion of P.gingivalis on Li-PLLA membranes was significantly lower than adhesion on pure PLLA membranes, particularly with regard to the 10%Li and 15%Li membranes. Significant antibacterial activity of Li-PLLA were also observed against according to the inhibition zone test.

Lithium carbonate accelerates the healing of periapical periodontitis

Lithiated porous silicon nanowires stimulate periodontal regeneration