But it's a wicked vicious circle.
Breakdown in gut barriers to bacteria may promote inflammation and craving in alcoholics
When patients were exposed to alcohol, the researchers found that the inflammatory response originated from gut-derived bacterial products that crossed the gut barrier, which in turn, activated specific inflammatory pathways in blood mononuclear cells.So alcohol increases gut permeability.
Prior to undergoing detoxification, the observed inflammation correlated with both alcohol consumption and alcohol craving among the alcohol-dependent patients. Following detoxification, some, but not all, of the altered inflammatory processes were either partially or fully recovered.
And Pneumonia does too.
And
Coinfection with Streptococcus pneumoniae Negatively Modulates Influenza-Specific CD8+ T Cell Response
Alcoholics have an abnormal CD8 T cell response to the influenza virus
"It has also been known since the 1800s that alcohol use disorders are associated with increased susceptibility to lung infection – both viral and bacterial, including community acquired pneumonia and tuberculosis – acute respiratory distress syndrome, and chronic obstructive pulmonary disease," added Ilhem Messaoudi, associate professor of biomedical sciences at University of California Riverside. "Therefore, understanding the mechanisms underlying the increased susceptibility to lung infection and injury in individuals with alcohol use disorder is extremely important. Although several studies have demonstrated that this phenomenon is in part due to significant perturbations in the immune system, our understanding of the impact of alcohol abuse on immunity remains incomplete."
Pneumonia promotes Flu infection and vice versa.
And
Pneumonia patients nearly twice as likely to suffer from depression, impairments
Which make you prone to drinking..
So then maybe you go in the hospital.
Pneumonia is the second most common hospital-acquired infection
Sepsis accounts for approximately 15% of hospital acquired infections.
Cognitive and Functional Decline Often Follow Severe Sepsis
And just so you clearly see the swirling vortex to hell-
People with Alzheimer's usually die of Pneumonia.
There are about 4 million Americans with the disease, and the average length of time between diagnosis and death is eight years, although people can live with the illness 20 years or more. As the disease progresses, patients lose the ability to coordinate basic motor skills such as swallowing, walking, or controlling bladder and bowel. Difficulty swallowing can cause food to be inhaled, which can result in pneumonia. Inability to walk can lead to bedsores. Incontinence can result in bladder infections... Such incapacitation again sets the stage for deadly infections. Doctors say it is possible that an Alzheimer's patient could progress to the point that damage from the disease to the centers of the brain that control breathing could cause death, but patients rarely get that far without an infection setting in. Once a patient is extremely incapacitated, there is little medical motivation to aggressively treat such infections.
They put you in a hospice bed, feed you pancakes and nobody brushes your teeth.
And you drown in septic delirium.
That was going to happen to me. For sure.
