A study published today in Nicotine & Tobacco Research demonstrates in a carefully controlled series of studies that the self-administration of nicotine by rats suppresses body weight gain independent of food intake.Like maybe Anti-inflammatory and Anti-Infective and Insulin Resistance Reducing Properties??????
The authors of the study investigated the impact of reducing nicotine doses on body weight, and results revealed that reduction of nicotine dose from a large self-administered dose to very low doses resulted in substantial weight gain. In rats self-administering a maximally-reinforcing dose of nicotine, body weight gain during the 20-day study period was attenuated by ~40% despite no change in food intake.
As lead author Laura Rupprecht said, "The findings are important in the context of potential product standards requiring very low nicotine levels in cigarettes, as they indicate that low nicotine levels may still reduce body weight, possibly motivating continued use and maintaining exposure to harmful chemicals in cigarette smoke."
The results of the four experiments in the study also indicate that the weight-suppression properties of nicotine may act through processes that are separate from those that contribute to nicotine addiction. A better understanding of the separate neurobiological mechanisms responsible for nicotine addiction and body weight regulation may allow for new avenues in the development of obesity pharmacotherapies.
Nicotine strengthens tight junctions in the intestine and prevents systemic bacterial infection.
It also reduces the immune reactions that are commonly called "Inflammation"
AND it improves glucose sensitivity.
All the data shows that the reason we smoke is to benefit from those beneficial properties of nicotine rather than the "Reward System" reinforcement they call addiction.
It's self medication of various infectious and metabolic illnesses.
And the reason we can't quit is because we get sicker if we do.
The correct conclusion from all this is that VAPING IS A VERY VIABLE THERAPY POSSIBILITY as it delivers the nicotine without all the damaging tar and particulates.
And one more time: I honestly believe Caffeine and Nicotine are the main reasons I am still alive.