Saturday, August 13, 2016

A Few for You

Period Pain Drug Can Cure Alzheimer’s Disease, New Study Suggests
This is a correlational study using behavioral metrics of mouse memory.   It has not been tested for anti-beta-amyloid effects, although most NSAIDs help reduce endotoxin effects somewhat.
Menstrual cramps seem to more attractive for headlines,   but Mefenamic acid is very commonly used for TOOTHACHES.  Head infections.  Go figure.

Botulinum toxin study proves possibility of remote effects
When Botox and related botulinum drugs entered the market, "the idea was that they are safe to use, they stay where they are injected, and you don't have to worry about toxin going to the central nervous system and causing weird effects," says Edwin Chapman, an investigator at the Howard Hughes Medical Institute and professor of neuroscience at the University of Wisconsin-Madison.
The concern that this powerful toxin can move beyond the injection site was reinforced in 2009, when the Food and Drug Administration added a prominent warning to prescribing information "to highlight that botulinum toxin may spread from the area of injection to produce symptoms consistent with botulism," including "unexpected loss of strength or muscle weakness. ... Understand that swallowing and breathing difficulties can be life-threatening and there have been reports of deaths related to the effects of spread of botulinum toxin."
In a study published today (Aug. 4, 2016) in Cell Reports, senior author Chapman, first author Bomba-Warczak and colleagues present clear evidence that toxin is moving between neurons in a lab dish.
Using VR technology, an exoskeleton and software, study claims participants have unexpectedly experienced partial recovery of movement and sensation.

Students in government-funded school meal programs at higher risk of being overweight 
"We found that the longer children were in the programs, the higher their risk of being overweight. We also saw the most negative effect of the government-funded school meal programs in the South, the Northeast, and rural areas of the country," You said. "The question now is what to do in order to not just fill bellies, but make sure those children consume healthy and nutritious food -- or at least not contribute to the obesity epidemic."
Not to mention insulin resistance contributes to cognitive problems....

Librarians Have an Olympics, Too


Endurance Starvation Was Once a Crowd-Pleasing Sport