Oh Fuck

Anyone on Suvorexant needs to discontinue usage right now!

I know most of us have the opposite problem, but you might know someone...

Insomnia is a flippin' picnic compared to having suppressed orexin levels and a wicked lung infection at the same time.
Those people may never recover .

Shit shit shit.

Orexin deficiency changes the hypothalamic immune response
The hypothalmic response to endotoxic challenge in orexin deficient animals is to cease orexin production altogether.
 
Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier 
Low orexin levels allow endotoxin from your microbiome to leak through your intestine into the bloodstream),  which causes even more orexin dysfunction.  (!!!!!)


PEOPLE ON XYREM NEED TO BE REALLY CAREFUL.
It is antiseptic, but you don't want to get snotty and be unable to breathe and unable to wake up at the same time.    I've never taken it though, please use your best judgement.