Thursday, November 12, 2026

Brain Tumors too.

 Identification of gingipains in glioblastoma tumors and evidence that P. gingivalis infection drives IL-6 and PD-L1 expression in glioma cells

Porphyromonas gingivalis—a key oral bacterium linked to chronic periodontitis and Alzheimer’s disease pathology—produces virulence factors found within glioblastoma tumor tissue.

It significantly boosts the invasiveness and migration of glioma cells in a viability-dependent manner.