Now this sort of makes sense

Lack of protein drives overeating

Humans' instinctive appetite for protein is so powerful that we are driven to continue eating until we get the right amount of protein, even if it means consuming far more energy than we need, according to new research from the University of Sydney's Charles Perkins Centre.

That sort of dovetails with this hypothesis. Eat enough carbs and fat, and you won't ever get a high enough level of protein.

But there's also binge eating caused by hypoglycemia.  Even with adequate protein intake.

Bacon and eggs will fill me up.
Bacon, eggs and pancakes will make me hungry all day.

This is Why

Depression is the second biggest cause of disability in the world

At this rate, it will be number one in another 10 years.

Another Good Example

Inflammation-Linked Diet Associated With Depression In Women 

Depression has been linked to diet since the dawn of civilization...

Freud is the doctor who claimed it was not.   About a hundred years ago.

The Unknown Unknowns

As I was saying...

New Ligament Discovered‬ In the Human Knee

Despite a successful ACL repair surgery and rehabilitation, some patients with ACL-repaired knees continue to experience so-called 'pivot shift', or episodes where the knee 'gives way' during activity. For the last four years, orthopedic surgeons Dr Steven Claes and Professor Dr Johan Bellemans have been conducting research into serious ACL injuries in an effort to find out why. Their starting point: an 1879 article by a French surgeon that postulated the existence of an additional ligament located on the anterior of the human knee.
That postulation turned out to be correct: the Belgian doctors are the first to identify the previously unknown ligament after a broad cadaver study using macroscopic dissection techniques. Their research shows that the ligament, which was given the name anterolateral ligament (ALL), is present in 97 per cent of all human knees. Subsequent research shows that pivot shift, the giving way of the knee in patients with an ACL tear, is caused by an injury in the ALL ligament.

This is a perfect example of doctors confidently acting despite the absence of information.
This is basic anatomy, people.   Should have been found a hundred years ago.
Nonetheless, surgeons have performed millions of these knee surgeries assuming they knew what they were doing.

Everything Old is New Again

Brain may play key role in development of type 2 diabetes

In their paper, the researchers note that about a century ago, scientists believed the brain played an important role in keeping glucose in check. But since its discovery in 1920, the focus shifted to insulin, and today nearly all treatments for diabetes are devised either to increase insulin or increase the body's sensitivity to the glucose-regulating hormone.

The researchers propose a two-system model - the pancreatic islet system reacts to rising blood glucose by releasing insulin, and the brain-centered system enhances insulin-dependent glucose metabolism while also stimulating glucose effectiveness independently of insulin.

According to the research, the brain system is the one most likely to fail first. This puts pressure on the islet system, which can compensate and carry on for a while, but then also fails, causing further decompensation in the brain system. The result is a vicious cycle of deterioration that ends in type 2 diabetes.

Emphasis mine.  The history of science is my true passion-  I am writing a book about how most of my ideas have been around for thousands of years.

Uh Huh

Vitamin D Deficiency Linked to Onset of Psychosis

Vitamin D deficiency is linked to first episodes of psychosis (FEP), new research suggests.
A study of almost 140 participants in the United Kingdom showed that those who were presenting to a psychiatric in-patient facility with an FEP had significantly lower levels of vitamin D than did their age-matched, healthy peers.
"What surprised us was the degree of difference between the patients and their matched controls, with patients being nearly 3 times as likely to have full-blown vitamin D deficiency," co–first author John Lally, MRCPsych, clinical research fellow in the IMPACT project at the Institute of Psychiatry in London, UK, and in the UK's National Psychosis Unit, told Medscape Medical News.

Here's the abstract.

I think this explains a whole lot of things.  Starting with Adam Lanza who spent his life in a basement playing video games...

All Hail the Germ Theory of Disease

Microbes in the Gut Help Determine Risk of Tumors

Transferring the gut microbes from a mouse with colon tumors to germ-free mice makes those mice prone to getting tumors as well, according to the results of a study published in mBio®, the online open-access journal of the American Society for Microbiology. The work has implications for human health because it indicates the risk of colorectal cancer may well have a microbial component.

Sounds simple enough.  Robert Koch used the same method to determine infectivity in the 1800's.   Somebody wanna tell me why this experiment wasn't done decades ago?????

Not Your Imagination

Non-Celiac Wheat Sensitivity: Is It an Allergy?
news article.

Here's the abstract.

Conclusions:

Patients with Non-Celiac Wheat Sensitivity and multiple food sensitivity show several clinical, laboratory, and histological characteristics that suggest they might be suffering from non-IgE-mediated food allergy. However, other pathogenic mechanisms need to be considered.

Funny how "allergy specialists" seem to be completely unaware that other antibody isotypes exist.   It is IgG mediated.  I'm sure of it.  Plenty of studies already in the literature.  That's the paper I'm researching now.   Including how they alter the microbial population and promote bacterial infections.

Expected Behavior

Shire hits new peak as ADHD drug succeeds in treating binge eating disorder

Vyvanse is just another amphetemine derivative.  Improves glycemic control.   SSDD.

Fun with Microbes

Exploring The Invisible Universe That Lives On Us — And In Us
   5:28 min video.    animated microbiome 101.   

Their Vision of Your Future

Speaking of trigeminal neuralgia...

Botox to Treat 'Suicide' Headaches

The gear they have developed looks a pistol with a very thin barrel, just the thickness of a knitting needle. The barrel is inserted up through the nose of the patient, and by passing through a natural hole in the nasal wall, the mouth of the barrel comes to a bundle of nerves behind the sinuses.  The surgeon pulls the trigger of the pistol, which shoots a dose of Botox to the area around the nerve bundle. The whole process takes about a half-an-hour.

Paralyze your brain.   Can't imagine what might go wrong...

related post     another link

The Price of Doing Business

Johnson & Johnson to pay $2.2 billion to end U.S. drug probes 

In one of the largest health care fraud settlements in U.S. history, Johnson & Johnson will pay $2.2 billion to end civil and criminal investigations into kickbacks to pharmacists and the marketing of pharmaceuticals for off-label uses, U.S. Attorney General Eric Holder said on Monday.

From 1999 through 2005, J&J and its subsidiary Janssen Pharmaceuticals Inc promoted Risperdal for unapproved uses, including controlling aggression and anxiety in elderly dementia patients and treating behavioral disturbances in children and in individuals with disabilities, according to the complaint.

Johnson & Johnson's conduct "recklessly put at risk" the health of children, dementia patients and others to whom the drug was prescribed at a time it was only approved by the U.S. Food and Drug Administration to treat schizophrenia, Holder said.

Just thought I would remind y'all that your good buddies over at Jazz are using their billions to nullify this law so they can sell their evil shit to all kinds of mentally impaired people without testing it first.

Bwa ha ha ha ha

Zombie shopping

Brain Eating Zombies of the Day

The American Heart Association.   All Day.  Every Day.

Brushing your teeth could prevent heart disease

Taking care of your gums by brushing, flossing, and regular dental visits could help hold heart disease at bay. Researchers at Columbia University's Mailman School of Public Health have shown for the first time that as gum health improves, progression of atherosclerosis slows to a clinically significant degree. Findings appear online in the Journal of the American Heart Association.

Yes, well your experiment does not clarify how those people with periodontal disease improved their condition. The standard treatment of acute periodontitis is chlorhexidine rinse and antibiotics, NOT brushing and flossing, which are clearly inadequate given the amount of atherosclerosis and dental pathology in this country.

Nice try, AHA and ADA.  SSDD.

Seriously

Scientists reduce behaviours associated with problem gambling in rats

This is a rather complex experiment, because first they have to make rats with gambling problems...
But the crucial sentence is at the end-

The D4 blocker drug used in the study has previously been tested on humans in attempts to treat behaviour disorders like schizophrenia but appeared to have no effect.

They have a drug.  They Must. Find. Someone. To. Sell. It. To.

Unfortunately for them-  compulsive Humans have been shown to have problems with their D2 receptors.

Brain Eating Zombie of the Day

Michael Kimmel

Why is it always a white guy: The roots of modern, violent rage 

He wrote an entire book about how the decline of white male power makes these guys angry.  Even though most of them are too young to remember white male dominance...

The fact is, caucasians are genetically much more likely to suffer from streptococcal infections.  And sugar consumption is at an all time high.   And young men are notorious about avoiding seeking health care unless their eyes are bleeding...

Holmes exhibits symptoms of Tourettes,  most of the rest show symptoms of trigeminal neuralgia. 

Dia de los Muertos

My housewarming gift to myself.   Zombie Ranching.

And my "costume".

For some reason, that reminds me

Back in the day- back when it was really bad-
I used to lie on the floor crying and think-  "I'm not feeling sorry for myself, I'm doing field research..."

My apologies

For neglecting this blog.   I know it seems like I don't do anything, but really, I'm thinking super hard right now.   All this cleaning must have kick-started my brain.    Really Good Things coming.  

Rock and Roll Heaven

The greatest love song ever written.

Rest in Peace, dear man.

As I was Saying

The first basic principle: Each person has their own combination of immune genes.
Some people are more susceptible to infections in general.
Others are susceptible to specific pathogens.

Scientists Discover Genetic Disease That Causes Recurrent Respiratory Infections

Know Hope

These are Days.

Just a Reminder

A sociopath chooses the path of plausible deniability.

Dear Dr. Dreamy

Thanks for contacting me.
One of the reasons I moved to Arizona is because it is sunny, warm and dry and a good climate for a person with darkness sensitivity, no brown fat and recurring respiratory infections.  The other reason is because it swarming with "medical professionals" making lots of money off the people like me who end up here when they're sick and tired.

I didn't realize that was your crazy clinic up there in the hills, but yeah- I have every intention of putting you out of business. 
You still want to hear my thoughts on Narcolepsy?

Old Song of the Day

I had to.