"He now lives within himself, which is a dangerous place for Donald Trump to be," says someone who speaks with the President. "I see him emotionally withdrawing. He's gained weight."Yes, we are definitely in the downward portion of the metabolic and mental symptoms.
One type of glial cell, called an astrocyte, prunes unnecessary synapses in the brain to remodel its wiring. Another type, called a microglial cell, prowls the brain for damaged cells and debris.Similarly-
Bellisi’s team found that after an undisturbed sleep, astrocytes appeared to be active in around 6 per cent of the synapses in the brains of the well-rested mice. But astrocytes seemed to be more active in sleep-deprived mice – those that had lost eight hours of sleep showed astrocyte activity in around 8 per cent of their synapses, while the cells were active in 13.5 per cent of the synapses of the chronically sleep-deprived animals.
This suggests that sleep loss can trigger astrocytes to start breaking down more of the brain’s connections and their debris. “We show for the first time that portions of synapses are literally eaten by astrocytes because of sleep loss,” says Bellesi.
Naviaux, who is co-director of the Mitochondrial and Metabolic Disease Center at UC San Diego, believes that ASD -- and several other chronic conditions, including chronic fatigue syndrome and some autoimmune disorders -- are caused by metabolic dysfunction or impaired communication between cells in the brain, gut and immune system.
Specifically, this dysfunction is caused by abnormal persistence of the cell danger response (CDR), a natural and universal cellular reaction to injury or stress. "The purpose of CDR is to help protect the cell and jump-start the healing process," said Naviaux, by essentially causing the cell to harden its membranes, cease interaction with neighbors and withdraw within itself until the danger has passed.
"But sometimes CDR gets stuck," Naviaux said. "This prevents completion of the natural healing cycle and can permanently alter the way the cell responds to the world. When this happens, cells behave as if they are still injured or in imminent danger, even though the original cause of the injury or threat has passed."
At the molecular level, cellular homeostasis or equilibrium is altered, creating an abnormal cellular response that leads to chronic disease. "When this happens during early child development," said Naviaux, "it causes autism and many other chronic childhood disorders."
As a person with a lifetime of experience with multiple types of hallucinations..."The problem is with the current news cycle is that it's hard to tell if you're hallucinating or not." Joy Anne Reid
(Duterte's) administration has overseen a brutal extrajudicial campaign that has resulted in the killings of thousands of suspected drug dealers.The most urgent drug problem in this country is caused by DOCTORS and PHARMAS handing out opiates to unsuspecting sick people.
Trump has not spoken out against that strategy, and in their call he praised Duterte for doing an “unbelievable job on the drug problem.”
“Many countries have the problem, we have the problem, but what a great job you are doing and I just wanted to call and tell you that,” Trump said, according to the transcript.
STAT reviewed decades of Trump’s on-air interviews and compared them to Q&A sessions since his inauguration. The differences are striking and unmistakable.My Hypothesis-
Tooth and Nasal infections (go figure)
Trump and Congressional Republicans have repeatedly said that the ACA is collapsing under its own weight, and that the exchanges are exploding. But while there is reason to be concerned about problems in the individual market, the story of Obamacare’s problems is not complete unless we take a look back over the last several years and look at all the ways Republican lawmakers, governors, and pundits – and now the Trump Administration – took steps to deliberately weaken the Affordable Care Act.
In a vote of 378 to 48, the House passed legislation to take power away from the current Librarian of Congress, Dr. Carla Hayden.
The legislation, H.R. 1695, was authored by House Judiciary Chairman Bob Goodlatte (D-Va.) and ranking member John Conyers (D-Mich.), would limit the powers of the librarian. It is expected to pass the Senate and be signed into law by President Trump.
The bill makes the head of the Copyright Office, the Register of Copyrights, a presidential appointment that would have to be confirmed by the Senate, rather than an appointment by the Librarian of Congress, as it has been since 1870. The bill also limits the position of Librarian of Congress to a ten-year term.
The previous Librarian of Congress, James Billington, served in the position for 28 years.
President Barack Obama appointed Hayden the 14th Librarian of Congress on February 24, 2016. She is the first African American to hold the position, as well as the first woman to be the Librarian of Congress, in the agency’s history. On March 23, legislation was introduced to block Hayden from appointing the next Register of Copyrights. That legislation passed the House on April 26.
Supporters of the bill argued that the legislation would help to modernize the Copyright Office and make it more accountable to Congress. Attempts to contact the office of Rep. John Conyers (D-Mich.) for details on why he authored H.R. 1695, were not answered.
“This bill serves no purpose other than to take power away from the Librarian of Congress and give it to powerful lobbyists, who will have a major say in who runs the Copyright Office,” wrote Michael Masnick on TechDirt.com on April 26. “It’s a bad bill, and it’s a gift to Hollywood.”
The entertainment industry pushed hard for the passage of H.R. 1695. It’s likely that the selection of the Librarian of Congress will be the focus of attention of the power of the entertainment lobby moving forward now that senators will play a role in confirmation.
You can work full time but not have the money to fix your teeth – visible reminders of the divide between rich and poor.
The long-term administration of low-doses of the cannabinoid tetrahydrocannabinol (THC), the main psychoactive ingredient in marijuana, ameliorates age-related learning and memory deficits in mice, researchers have observed.Sounds like my kind of research...
On the basis of this observation, the investigators plan to conduct a clinical trial to determine whether the finding applies to elderly individuals with and those without cognitive impairment, Andras Bilkei-Gorzo, PhD, of the Institute of Molecular Psychiatry, the University of Bonn, Germany, told Medscape Medical News.
Dr Bilkei-Gorzo and colleagues examined the effects of long-term, low-dose THC administration in young (2 months old), mature (12 months old), and old (18 months old) mice.
They found that THC treatment was associated with impaired behavioral performance on learning and memory tasks in young mice, but was associated with improved learning and memory in mature and old mice.
"THC treatment has practically the opposite effect in young and old animals," Dr Bilkei-Gorzo told Medscape Medical News.
"The same treatment rejuvenated old brains, whereas it made the young brains old. The reason of this phenomenon is that the activity of cannabinoid system declines in aging. In old animals, THC treatment restored the failing cannabinoid system activity, whereas it overactivated the normally functioning cannabinoid system in young animals," the researchers write.
Bob Owens, editor of the popular pro-gun blog BearingArms.com, died Monday in an apparent suicide, authorities say.
Owens was found around 11 a.m. near a stop sign outside his subdivision in Fuquay-Varina, N.C., a town southwest of Raleigh. A gun was located nearby, according to the Fuquay-Varina Police Department.
An autopsy to determine the cause of death is still pending, but police said the gunshot wound was “possibly … self-inflicted.”
Shortly before Owens’s death, he apparently wrote a chilling message on Facebook: “In the end, it turns out that I’m not strong. I’m a coward, and selfish son of a b‑‑‑‑. I’m sorry.”
Martha McSally stood up in GOP conference meeting and said "Let's get this fucking thing done". Yes, direct quote — per members and aides.
Under the GOP's health plan, Sexual Assault and Domestic Abuse could be considered preexisting conditions.
